Clinical Trial: Evaluation of the Role of OCT in the Detection of HIV-associated Neurocognitive Disorder
Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional
Official Title: Evaluation of the Role of Optical Coherence Tomography (OCT) in the Detection of HIV-associated Neurocognitive Disorder
Brief Summary: The purpose of this study is to determine the sensitivity and specificity of the use of optical coherence tomography to detect HIV-associated neurocognitive disorder compared to MRI and usual cognitive screening tools.
Detailed Summary:
Sponsor: Centre Hospitalier Universitaire Saint Pierre
Current Primary Outcome: Number of patients with abnormal OCT (retinal thickness in µm) in patients with abnormal full neurocognitive evaluation [ Time Frame: Baseline ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Number of patients with abnormal neuroscreen and/or modified dementia scale in patients with abnoraml full neurocognitve evaluation [ Time Frame: Baseline ]
- Correlation between retinal thickness (in µm) and cerebral atrophy in % of brain parenchymal fraction ( measured by cerebral MRI) [ Time Frame: Baseline ]
Original Secondary Outcome: Same as current
Information By: Centre Hospitalier Universitaire Saint Pierre
Dates:
Date Received: April 22, 2015
Date Started: April 2015
Date Completion: December 2016
Last Updated: January 27, 2016
Last Verified: January 2016
