Clinical Trial: Iron Overload Assesment in Sickle Cell Anemia and Sickle Cell Thalassemia

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Clinical and Laboratory Assessment of Iron Overload in Sickle Cell Anemia and Sickle Cell Thalassemia Using T2* Cardiac MRI.

Brief Summary: Iron overload is well study in Thalassemia patients and it's not only related to blood transfusions, since intestinal iron absorption is also increased in those patients. Sickle cell patients didn't develope significant clinical symptoms and signs of iron overload in spite frequent transfusions. The purpouse of this study is to assess the iron overload in Sickle cell anemia and Sickle cell Thalassemia patients using clinical parameters and cardiac T2*MRI in order to determine the cardiac and liver iron.

Detailed Summary:
Sponsor: HaEmek Medical Center, Israel

Current Primary Outcome: Assessment of Iron overload. [ Time Frame: December 2008 ]

Original Primary Outcome: Assessment of Iron overload.

Current Secondary Outcome: Institute the criteria for iron chelator treatment [ Time Frame: December 2008 ]

Original Secondary Outcome: Institute the criteria for iron chelator treatment

Information By: HaEmek Medical Center, Israel

Dates:
Date Received: August 5, 2007
Date Started: September 2007
Date Completion:
Last Updated: August 25, 2011
Last Verified: August 2011