Clinical Trial: Parathyroid Hormone for the Treatment of Humerus Fractures
Study Status: Recruiting
Recruit Status: Unknown status
Study Type: Interventional
Official Title: Phase IV Study of the Effect of Parathyroid Hormone on Fractures of the Humerus
Brief Summary:
Hypothesis:
The investigators want to study whether parathyroid hormone improves healing of humerus after a fracture. The investigators will assess healing of the humerus with Constant score.
Detailed Summary:
Sponsor: Hvidovre University Hospital
Current Primary Outcome: Changes in constant score [ Time Frame: 5, 8, 11, 23, and 104 weeks. ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Changes in Oxford Shoulder Score [ Time Frame: 5, 8, 11, 23, and 104 weeks. ]Oxford shoulder score is a questionnaire that assesses the function of the arm through the evaluation of the participant.
- Changes in bone formation evaluated by X-ray. [ Time Frame: 5, 8, 11, 23, and 104 weeks. ]
- Changes in biochemical bone markers [ Time Frame: 0, 5, 25 weeks ]sodium, potassium, creatinine, liver enzymes, vitamin D, parathyroid hormone, alkaline phosphatase, hemoglobin, magnesium, calcium, zinc.
- Changes in regulatory T lymphocytes [ Time Frame: 0, 8, 24 weeks ]Regulatory CD3+CD4+CD25+Foxp3+ T lymphocytes.
Original Secondary Outcome: Same as current
Information By: Hvidovre University Hospital
Dates:
Date Received: March 12, 2012
Date Started: March 2012
Date Completion: December 2013
Last Updated: September 13, 2012
Last Verified: September 2012