Clinical Trial: Life Quality and Health in Patients With Klinefelter Syndrome

Study Status: Completed
Recruit Status: Completed
Study Type: Observational

Official Title: Life Quality and Health in Patients With Klinefelter Syndrome - a Questionnaire Survey

Brief Summary:

Klinefelter syndrome is the most common sex-chromosome disorder in men with a prevalence of 1 in 660 men. The syndrome is associated with hypogonadism. Many patients with Klinefelter syndrome have psychological complaints and physical discomfort. Some patients report a positive effect of testosterone treatment, whereas others do not.

The aim of this study is:

(i) To investigate quality of life in patients with Klinefelter syndrome. (ii) To investigate functional, physical and mental health in patients with Klinefelter syndrome.

Questionnaire concerning mental and physical health and life quality are sent out to patients with KS and to age-, educational- and zipcode-matched men from the general population. The questionnaire include questions about housing, income, marital status, fatherhood, medication, chronic disease,school and education, attachment to the labor, sexual and erectile function, life quality, mental and physical health, satisfaction with life and symptoms of attention deficits hyperactivity disorders.


Detailed Summary:
Sponsor: University of Aarhus

Current Primary Outcome:

  • Quality of life [ Time Frame: 3 month ]
    Quality of life score is measured with the WHOQOL-Brief questionnaire
  • Satisfaction with life [ Time Frame: 3 month ]
    Satisfaction with life is measured with the SWLS - Satisfaction with Life Scale
  • ADHD symptoms [ Time Frame: 3 month ]
    ADHD symptoms are measured by Adult ADHD Self-Report Scale (ASRS-v1.1) Symptom Checklist
  • General health [ Time Frame: 3 month ]
    General health is measured by SF-36 questionnaire
  • Erectile function [ Time Frame: 3 month ]
    Erectile function is measured by the International index of erectile function (IIEF-5) as a diagnostic tool for erectile function.


Original Primary Outcome:

  • Quality of life [ Time Frame: 3 month ]
    Quality of life score is measured with the WHOQOL-Brief questionnaire
  • Satisfaction with life [ Time Frame: 3 month ]
    Satisfaction with life is measured with the SWLS - Satisfaction with Life Scale
  • ADHD symptoms [ Time Frame: 3 month ]
    ADHD symptoms are measured by Adult ADHD Self-Report Scale (ASRS-v1.1) Symptom Checklist
  • General health [ Time Frame: 3 month ]
    General health is measured by SF-36 questionnaire
  • Erectile function [ Time Frame: 3 month ]
    Erectile function is measrued by the International index of erectile function (IIEF-5) as a diagnostic tool for erectile function.


Current Secondary Outcome:

Original Secondary Outcome:

Information By: University of Aarhus

Dates:
Date Received: September 11, 2012
Date Started: September 2012
Date Completion:
Last Updated: May 31, 2015
Last Verified: September 2012