Clinical Trial: Septic Encephalopathy and Late Cognitive Dysfunction

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Septic Encephalopathy and Late Cognitive Dysfunction in Patients With Sepsis - the Role of Inflammation

Brief Summary:

Delirium and long-term cognitive dysfunction are important problems in intensive care patients. Patients with sepsis are at a high risk of developing delirium (septic encephalopathy), which may be an important risk factor for the development of long-term cognitive dysfunction.

Working hypotheses: 1. Septic encephalopathy and cognitive dysfunction are caused by an unspecific reaction of the brain to an intense inflammatory stimulus. 2. It is possible to therapeutically influence the inflammatory response and its effects on the brain.

Detailed Summary:
Sponsor: University Hospital, Basel, Switzerland

Current Primary Outcome:

Original Primary Outcome:

Current Secondary Outcome:

Original Secondary Outcome:

Information By: University Hospital, Basel, Switzerland

Dates:
Date Received: October 14, 2008
Date Started: October 2008
Date Completion:
Last Updated: March 9, 2015
Last Verified: March 2015