Clinical Trial: Effectiveness of Training in Reading Rehabilitation for Patients With Diabetic Macular Oedema
Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional
Official Title: Effectiveness of Training in Reading Rehabilitation for Patients With Diabetic Macular Oedema (DMO)- Randomized Controlled Trial
Brief Summary:
Diabetic macular oedema (DMO) is a sight-threatening problem for diabetic patient who has swelling in macula. Patients with DMO can receive laser treatment and achieve good acuity finally. However, some patients still have difficulties in reading even after proper treatment.
In this project, the investigators aimed to explore the effectiveness of different training paradigms in improving reading performance in patients with DMO.
Detailed Summary:
Patients with diabetic macular oedema (DMO), after receiving laser photocoagulation, achieved good outcomes in distance acuity. However, some patients, particularly those developing parafoveal scotoma, still had difficulty in reading. Inability to read or reading very slowly leads to the potential loss of job, as well as the enjoyment of reading for leisure.
In this study, the investigators aimed to investigate the effectiveness of reading rehabilitation using perceptual learning paradigms in enhancing reading performance in patients with reading difficulties due to DMO. Also, the fundamental mechanisms explaining the reading problems in patients with DMO reading Chinese will be examined.
The investigators hypothesize that the perceptual training would show an improvement in reading. The investigators' primary hypothesis is that temporal visual processing speed and spatial visual span will be improved after perceptual training. The investigators' secondary hypothesis is that the reading speed and fixation stability will be improved after training.
Sponsor: The Hong Kong Polytechnic University
Current Primary Outcome:
- Change in visual processing speed [ Time Frame: Change from baseline at week 6 and change from baseline at week 12 week ]Using trigrams to measure the character-recognition accuracy while characters are presented at different exposure times
- Change in visual span size [ Time Frame: Change from baseline at week 6 and change from baseline at week 12 week ]Using trigrams to measure the character-recognition accuracy while characters are presented at different positions
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Change in reading performance [ Time Frame: Change from baseline at week 6 and change from baseline at week 12 week ]
Measured in three different ways for Chinese:
- Rapid serial visual presentation (RSVP)
- Sentence reading (MNREAD)
- Passage reading (IReST)
- Change in fixation stability [ Time Frame: Change from baseline at week 6 and change from baseline at week 12 week ]Fixation stability will be measured by MP-1 microperimeter.
- Change in Chinese version of Impact of Visually Impaired (C-IVI) measure [ Time Frame: Change from baseline at week 6 and change from baseline at week 12 week ]Self evaluated instrument to measure vision related restriction of participation in daily living.
Original Secondary Outcome: Same as current
Information By: The Hong Kong Polytechnic University
Dates:
Date Received: May 25, 2015
Date Started: May 2015
Date Completion: December 2017
Last Updated: February 17, 2016
Last Verified: February 2016
