Clinical Trial: Evaluation of Efficacy and Safety of Long-acting Risperidone Microspheres in Patients With Schizophrenia or Other Psychotic Disorders When Switching From Typical Antipsychotic (Oral/Depot) or Atypical Oral Other Than Risperidone
Study Status: Completed
Recruit Status: Unknown status
Study Type: Interventional
Official Title: Evaluation of Efficacy and Safety of Long-acting Risperidone Microspheres in Patients With Schizophrenia or Other Psychotic Disorders When Switching From Typical Antipsychotic (Oral/Depot) or Atypical
Brief Summary: The purpose of this study is to evaluate the efficacy, tolerability and safety of patients on long-acting Risperidone microshpheres injection. The major advantage of long-acting injection over oral medication is facilitation of compliance in medication taking. Non-compliance is very common among schizophrenic and is a frequent cause of relapse.
Detailed Summary:
Sponsor: Hospital Authority, Hong Kong
Current Primary Outcome:
- Efficacy/ Clinical Global Impression [ Time Frame: Week 0, 4, 8,12 ]
- Personal and Social Performance Scale [ Time Frame: Week 0, 12 ]
- Extrapyramidal Symptom [ Time Frame: Week 0, 4, 8,12 ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- +Quality of life SF-36 [ Time Frame: Week 0,12 ]
- Pain assoicated with injection VAS [ Time Frame: Week 0, 4, 8, 12 ]
Original Secondary Outcome: Same as current
Information By: Hospital Authority, Hong Kong
Dates:
Date Received: November 21, 2007
Date Started: October 2004
Date Completion: November 2005
Last Updated: July 6, 2010
Last Verified: July 2010
