Clinical Trial: Nicotine Treatment for Pulmonary Sarcoidosis: A Clinical Trial Pilot Study
Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional
Official Title: Nicotine Treatment for Pulmonary Sarcoidosis: A Clinical Trial Pilot Study
Brief Summary: The purpose of this study is to determine if nicotine treatment is beneficial for the treatment of sarcoidosis. Sarcoidosis is a disease of unknown cause that leads to inflammation. This disease affects your body's organs.
Detailed Summary:
Participants will be randomly divided into two groups. One group will receive a nicotine patch to use for approximately 7 months; the other group will receive placebo for nicotine patches to use for the same time period.
Both groups will be contacted weekly by phone for the first 3 weeks then monthly for the duration of the study to monitor for any side effects.
The following information and samples will be collected:
Questionnaires Medical History Spirometry CT Scans Physical Exam Blood Samples for nicotine and nicotine metabolites
Sponsor: Ohio State University
Current Primary Outcome: Spirometry [ Time Frame: 28 weeks ]
Original Primary Outcome: Same as current
Current Secondary Outcome: computed tomography (CT) [ Time Frame: 28 weeks ]
Original Secondary Outcome: Same as current
Information By: Ohio State University
Dates:
Date Received: October 10, 2014
Date Started: October 2014
Date Completion: October 2019
Last Updated: January 9, 2017
Last Verified: January 2017