Clinical Trial: Investigation of the Efficacy of Antibiotics on Pulmonary Sarcoidosis
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: Investigation of the Efficacy of Antibiotics on Pulmonary Sarcoidosis
Brief Summary: Sarcoidosis is a granulomatous disease for which the molecular and immunologic association with mycobacteria continues to strengthen. The investigators are interested in conducting a proof-of-concept investigation of the effects of antibiotics on sarcoidosis resolution. The investigators hypothesize that pulmonary sarcoidosis will improve faster if patients are given antimycobacterial therapy, in addition to their standard therapy.
Detailed Summary:
Sponsor: Vanderbilt University
Current Primary Outcome: Change in Absolute FVC From Baseline to Post Completion of 8 Weeks of Antibiotic Therapy. [ Time Frame: 8 weeks ]
Original Primary Outcome: To assess the efficacy and safety of antimycobacterial therapy in patients with pulmonary sarcoidosis. [ Time Frame: 1 year ]
Current Secondary Outcome:
Original Secondary Outcome:
Information By: Vanderbilt University
Dates:
Date Received: July 22, 2010
Date Started: July 2010
Date Completion:
Last Updated: October 26, 2012
Last Verified: October 2012