Clinical Trial: A Working Memory Training to Decrease Rumination in Depressed and Anxious Individuals

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: A Working Memory Training to Decrease Rumination in Depressed and Anxious Individuals: A Double-blind Randomized Controlled Trial

Brief Summary: Dysfunctioning executive functioning, including working memory (WM), is related to rumination. Findings show that working memory capacity (WMC) can be increased by training. The current study explored by means of a double-blind randomized controlled trial whether an adaptive WM training could reduce rumination, anxiety and depression in a sample of 98 depressed and anxious individuals.

Detailed Summary:
Sponsor: Erasmus Medical Center

Current Primary Outcome: Change in Ruminative Response Scale (RRS) score from pre to post training and after two months (follow up 2) [ Time Frame: Pre training (baseline), post training (4 weeks after baseline, training starts 1 day after baseline) and follow-up (2 months after post-test) ]

Dutch version; Raes, Hermans, & Eelen, 2003) measures the frequency of self-reported rumination behavior, with answer options ranging from 1 (never) to 4 (always). The total score of the 22 items was used in the analyses.


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Change in Beck Depression Inventory Second Edition (BDI-II) score from pre to post training and after two months (follow up 2) [ Time Frame: Pre training (baseline), post training (4 weeks after baseline, training starts 1 day after baseline) and follow-up (2 months after post-test) ]
    The Beck Depression Inventory - II (BDI-II; Beck, Steer, & Brown, 1996; Dutch version: Van der Does, 2002) measures the severity of depression symptoms of the last two weeks.
  • Change in State-Trait Anxiety Inventory (STAI) score from pre to post training and after two months (follow up 2) [ Time Frame: Pre training (baseline), post training (4 weeks after baseline, training starts 1 day after baseline) and follow-up (2 months after post-test) ]
    The State-Trait Anxiety Inventory (STAI; Spielberger, Gorsuch, Lushene, Vagg, & Jacobs, 1983, Dutch version; Van der Ploeg, Defares, & Spielberger, 1979) measures self-reported anxiety, divided in state anxiety and trait anxiety.


Original Secondary Outcome: Same as current

Information By: Erasmus Medical Center

Dates:
Date Received: April 8, 2014
Date Started: August 2011
Date Completion:
Last Updated: April 18, 2014
Last Verified: April 2014