Clinical Trial: Correlation Between Clinical and Electrophysiological Phenotypes in a Population of Patients With Neuropathy Charcot-Marie-Tooth Disease Type 1A
Study Status: Completed
Recruit Status: Unknown status
Study Type: Observational
Official Title: Correlation Between Clinical and Electrophysiological Phenotypes in a Population of Patients With Neuropathy Charcot-Marie-Tooth Disease Type 1A
Brief Summary: This exploratory cross-sectional study proposes, firstly, to objectify in a population of Charcot-Marie-Tooth disease type 1A (CMT 1A)if there is a correlation between the recording of electrical parameters and upper limb muscle strength of the thigh and in a second step, to seek a relationship between the measured parameters.
Detailed Summary:
Patients suffering from CMT 1A neuropathy will be invited to go through a series of tests such as:
- Electromyography
- Isokinetic test
- Podiatric assessment
- Functional evaluations: Hand dexterity, limbs muscles strength
- Quality of life assessment with questionnaires
Sponsor: University Hospital, Clermont-Ferrand
Current Primary Outcome: axonal loss [ Time Frame: at day 1 ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Muscle strength [ Time Frame: at day 1 ]
- Functional scores [ Time Frame: at day 1 ]
- Hand testing [ Time Frame: at day 1 ]
- spatial and temporal parameters of walking [ Time Frame: at day 1 ]
- Barometric stabilometric podo-static scores [ Time Frame: at day 1 ]
- Quality of life [ Time Frame: at day 1 ]
- Fatigue [ Time Frame: at day 1 ]
- Depression [ Time Frame: at day 1 ]
Original Secondary Outcome: Same as current
Information By: University Hospital, Clermont-Ferrand
Dates:
Date Received: November 16, 2012
Date Started: December 2012
Date Completion: December 2013
Last Updated: December 13, 2012
Last Verified: December 2012
