Clinical Trial: Nasal Saline Irrigation After Radiation Therapy for Oropharyngeal Cancer

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Nasal Saline Irrigation After Radiation Therapy for Oropharyngeal Cancer: A Pilot Study

Brief Summary: The purpose of this study is to learn whether nasal saline irrigation is beneficial to patients undergoing radiation therapy for oropharyngeal cancer.

Detailed Summary: In this study, subjects are randomized to one of two study arms. They are either randomized to receive nasal saline irrigation treatment (treatment group) or not to receive any nasal irrigation treatment (control group). Subjects randomized to the treatment group will be provided with saline packets to mix with water. All study subjects will be asked to complete questionnaires during the study. If a subject completes all study related activities, their total length of participation in the study will last about 2 months.
Sponsor: Lisa Shnayder

Current Primary Outcome: Change in quality of life, measured using Sino-Nasal Outcome Test (SNOT-20) summary scores [ Time Frame: Change from Baseline to Month 2 ]

Outcome measured using Sino-Nasal Outcome Test (SNOT-20) summary scores. Scores will be collected at the baseline visit and again on the Month 2 visit. Outcome represented as a change in mean summary scores between the two visits. Scores can range from 0-5 with 0 being the best and 5 being the worst.


Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: University of Kansas Medical Center

Dates:
Date Received: January 9, 2015
Date Started: January 2013
Date Completion:
Last Updated: November 2, 2015
Last Verified: November 2015