Clinical Trial: Exertional Rhabdomyolysis- Characterization of Prediction Tests for Return to Duty
Study Status: Not yet recruiting
Recruit Status: Not yet recruiting
Study Type: Interventional
Official Title: Exertional Rhabdomyolysis- Characterization of Prediction Tests for Return to Duty
Brief Summary: In order to determine norm values for skeleton muscle disassembly due to physical exertion in healthy and trained population, and developing a prediction test for approval for rhabdomyolysis injuries to return to duty, 50 healthy subjects will undergo a series of different physical tests.
Detailed Summary: 50 healthy civilians volunteers will be recruited for this study. Each subject will undergo the physical tests: anthropometric measurements, wingate test, VO2max test, step test and running on the anaerobic threshold, on separate days. Blood sample, lactic acid level (measured in blood drop - finger sting) and urine sample will be taken before and after every test.
Sponsor: Sheba Medical Center
Current Primary Outcome:
- creatine phosphokinase (CPK) [ Time Frame: 5 experiment days for each subject ]CPK is a marker for muscle damage assessed in blood test. blood sample will be taken before and after step test and running on the anaerobic threshold test.
- oxygen consumption (VO2) [ Time Frame: 5 experiment days for each subject ]VO2 will be monitored continuously using a metabolic system (ERGOTEST 680, ZAN, GERMANY ) during VO2max test, step test and running on the anaerobic threshold test.
Original Primary Outcome: Same as current
Current Secondary Outcome:
- lactic acid [ Time Frame: 5 experiment days for each subject ]lactic acid level is assessed from blood drop (finger sting), will be taken before and after every test. lactic acid is a marker for anaerobic effort evaluating.
- Myoglobin [ Time Frame: 5 experiment days for each subject ]marker from urine sample, taken before and after step test and running on the anaerobic threshold test.
- Heart rate [ Time Frame: 5 experiment days for each subject ]The heart rate will be monitored using a wearable heart rate monitor (Polar® sensor and heart rate monitor watch).
Original Secondary Outcome: Same as current
Information By: Sheba Medical Center
Dates:
Date Received: July 13, 2015
Date Started: October 2015
Date Completion: December 2016
Last Updated: July 14, 2015
Last Verified: July 2015