Clinical Trial: Comparison of Breathing Pattern During Neurally Adjusted Ventilatory Assist Ventilation and Pressure Support Ventilation
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: Comparison of Breathing Pattern During PSV and NAVA
Brief Summary: Comparison of Breathing pattern during mechanical ventilation. Two modes of mechanical ventilation are compared (Pressure Support Ventilation and Neurally Adjusted Ventilatory Assist)
Detailed Summary:
Eligibility : healthy subject without respiratory complications in the past
Subjects will breath spontaneously without mechanical ventilation, with Pressure Support Ventilation and with Neurally Adjusted Ventilatory Assist during.
Three levels of pressurisation will be tested : 5 cmH2O, 8 cmH2O and 12 cmH2O Duration of each condition will be about 15 minutes.
Measurements will include:Flow, airway pressure, SaO2, PtCO2, diaphragmatic electromyography, chest wall motion by optoelectronic plethysmography
Sponsor: Centre d'Investigation Clinique et Technologique 805
Current Primary Outcome: Comparison of breathing pattern during pressure support and Neurally Adjusted Ventilatory Assist (NAVA) [ Time Frame: 2h ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Tidal volume evaluated by optoelectronic plethysmography [ Time Frame: 2h ]
- Electrical diaphragmatic activity recorded by mechanical ventilator [ Time Frame: 2h ]
Original Secondary Outcome: Same as current
Information By: Centre d'Investigation Clinique et Technologique 805
Dates:
Date Received: June 6, 2012
Date Started: May 2012
Date Completion:
Last Updated: April 11, 2013
Last Verified: April 2013
