Clinical Trial: Anal Fistula Repair With Platelet-rich Plasma
Study Status: Withdrawn
Recruit Status: Withdrawn
Study Type: Interventional
Official Title: Anal fistUla Repair With Platelet-Rich plasmA (AURoRA)
Brief Summary:
Anal fistula is a very common disease with a high impact on life quality. The only commonly accepted treatment option is surgery. A wide range of operations and techniques have been developed all suffering from a relatively high recurrence rate.
The investigators propose the combination of the mucosal advancement flap with application of platelet-rich plasma (PRP) in the fistulectomy site. This study aims to test the hypothesis that by applying PRP the healing rate of complicated anal fistulas can be improved in comparison to a control group where the operation is performed without addition of PRP.
Detailed Summary:
Sponsor: University Hospital, Basel, Switzerland
Current Primary Outcome: Healing rate [ Time Frame: 2 Years ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Influence of risk factor smoking on healing rate [ Time Frame: 2 years ]
- Influence of risk factor high BMI on healing rate [ Time Frame: 2 years ]
- Influence of risk factor chronic renal failure on healing rate [ Time Frame: 2 years ]
- Influence of sex on healing rate [ Time Frame: 2 years ]
Original Secondary Outcome: Same as current
Information By: University Hospital, Basel, Switzerland
Dates:
Date Received: December 19, 2014
Date Started: November 2015
Date Completion:
Last Updated: February 5, 2016
Last Verified: February 2016
