Clinical Trial: A Comparison of MRI Perfusion and FDG PET/CT to Distinguish Between Radiation Injury and Tumor Progression
Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional
Official Title: Enhancing Brain Lesions After Radiation Therapy: A Comparison of MRI Perfusion and FDG PET/CT to Distinguish Between Radiation Injury and Tumor Progression
Brief Summary:
This study will examine if MRI perfusion and PET/CT can tell growing tumor and radiation injury apart. MRI perfusion looks at the blood vessels in the tumor. PET/CT looks if the tumor cells are actively growing. The investigators will do these two tests and see which one is better.
Optional Second MRI Perfusion
The investigators may ask the patient to undergo a second MRI perfusion scan. They are testing this second scan to see how well it works. It can cover the entire brain. It takes about an 5 extra minutes in the scanner. If they decide to undergo this second scan, they will divide the usual IV contrast dose into two parts. The patient will not receive extra IV contrast for this second scan. This second scan is optional.
Detailed Summary:
Sponsor: Memorial Sloan Kettering Cancer Center
Current Primary Outcome: imaging techniques [ Time Frame: 2 years ]
Original Primary Outcome: Same as current
Current Secondary Outcome: predicting tumor progression [ Time Frame: 2 years ]
Original Secondary Outcome: predicting tumor progression [ Time Frame: 2 years ]
Information By: Memorial Sloan Kettering Cancer Center
Dates:
Date Received: May 21, 2012
Date Started: May 2012
Date Completion: May 2018
Last Updated: December 19, 2016
Last Verified: December 2016