Clinical Trial: Comparison of Instillation and Packing in Mydriasis for Premature Infants

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Comparison of Conventional Instillation and Lower Conjunctival Fornix Packing in Mydriasis for Premature Infants

Brief Summary: The purpose of this study is to compare the mydriatic effect of 2.5% phenylephrine and 1% tropicamide by conventional instillation and lower conjunctival fornix packing in premature infants.

Detailed Summary: Adequate pupil dilatation was needed for screening and treatment of retinopathy of prematurity (ROP) in premature infants.In general clinical practice, mydriatic drugs were instilled many times until the pupil reached the maximum size. However, poor mydriasis were found in many eyes despite maximum instillation was used. From the clinical observation, we found the packing of mydriatic drugs in lower conjunctival fornix was much more effective to dilate the pupil than instillation in some patients. The purpose of this study was to compare the mydriatic effect of 2.5% phenylephrine and 1% tropicamide by conventional instillation and lower conjunctival fornix packing in premature infants.
Sponsor: Khon Kaen University

Current Primary Outcome: The primary outcome measure was the horizontal pupil diameter measured with a ruler in millimeters [ Time Frame: 40 minutes after mydriatric drugs ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Khon Kaen University

Dates:
Date Received: April 6, 2009
Date Started: March 2009
Date Completion:
Last Updated: March 7, 2012
Last Verified: March 2012