Clinical Trial: NT-proBNP as a Tool for the Detection of Acute Pulmonary Artery Embolism (APE)

Study Status: Completed
Recruit Status: Completed
Study Type: Observational

Official Title: NT-proBNP: a Useful Tool for the Detection of Acute Pulmonary Artery Embolism in Post-surgical Patients

Brief Summary: In patients with suspected APE (Acute Pulmonary Embolism) referred to the intensive care unit (ICU)after major surgery, serum NT-proBNP (N-terminal proBNP), Troponin-I and D-dimers were measured according to the standard hospital protocol. To definitively confirm or exclude APE, all patients underwent an angiographic CT-scan of the thorax.

Detailed Summary:

In patients with suspected APE referred to the intensive care unit after major surgery, serum NT-proBNP, Troponin-I and D-dimers were measured according to the standard hospital protocol. Blood samples were obtained within one hour after the onset of clinical symptoms.

Definitive confirmation or exclusion of APE was performed with an angiographic CT-scan of the thorax.

Sponsor: University of Ulm

Current Primary Outcome: Acute pulmonary embolism: CT-proof yes vs. no [ Time Frame: 1 hour after onset of clinical symptoms ]

Original Primary Outcome: Acute pulmonary embolism: CT-proof yes vs. no [ Time Frame: 1h after onset of clinical symptoms ]

Current Secondary Outcome:

Original Secondary Outcome:

Information By: University of Ulm

Dates:
Date Received: June 28, 2012
Date Started: November 2008
Date Completion:
Last Updated: July 4, 2012
Last Verified: July 2012