Clinical Trial: Optimizing Protein Intake and Nitrogen Balance in Adult Critically Ill Patients

Study Status: Not yet recruiting
Recruit Status: Not yet recruiting
Study Type: Interventional

Official Title: Optimizing Protein Intake and Nitrogen Balance in Adult Critically Ill Patients: a Randomized Controlled Trial (OPINiB STUDY)

Brief Summary:

The purposes of the study are:

  • To strictly ensure the appropriate level of protein and caloric provision in critical illness, according to the latest literature recommendation;
  • To determine if an association exists between protein intake and nitrogen balance in the context of a nutrition with appropriate protein provision based on the latest literature recommendations, rather than in a standard diet with a caloric target weight-based. Creatinine clearance will also be evaluated to determine if there is any harmful effect to the kidney secondary to an elevated BUN.
  • To determine if there is a difference in ICU mortality rate between the current nutrition standard and a hyperproteic nutrition protocol.

Detailed Summary:
Sponsor: University of Padova

Current Primary Outcome: nitrogen balance (gr) [ Time Frame: change from baseline through study completion, an average of 15 days ]

(gr)


Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: University of Padova

Dates:
Date Received: November 28, 2016
Date Started: December 2016
Date Completion: June 2017
Last Updated: December 9, 2016
Last Verified: December 2016