Clinical Trial: Synovial Aspiration and Serological Testing in Two-stage Revision Arthroplasty of Prosthetic Joint Infection

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational

Official Title: Benefit of Synovial Aspiration and Serological Testing in Two-stage Revision Arthroplasty of Prosthetic Joint Infection

Brief Summary:

The two-stage protocol is gold standard in terms of infection control treating prosthetic joint infections of total hip and total knee arthroplasty. The antibiotic pause for diagnostic reasons before reconstruction (stage two) is discussed concerning persistence of infection and development of resistant bacterial strains. Serological markers and synovial analysis are common use to exclude persistence of infection.

The investigators therefore asked 1) is the serological testing of c-reactive protein and leukocytes a valuable tool to predict a persistence of infection and 2) what is the role of synovial aspiration of PMMA Spacers on hip and knee joints.

Detailed Summary:
Sponsor: Technische Universität München

Current Primary Outcome: Reinfection rate [ Time Frame: 2 years ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Technische Universität München

Dates:
Date Received: January 30, 2017
Date Started: November 1, 2016
Date Completion: May 1, 2019
Last Updated: April 24, 2017
Last Verified: January 2017