Clinical Trial: Efficacy Study of Tamsulosin and Tolterodine Treatment for Chronic Prostatitis
Study Status: Completed
Recruit Status: Unknown status
Study Type: Interventional
Official Title: Efficacy Study of Tamsulosin and Tolterodine Treatment of Men With Chronic Prostatitis/Chronic Pelvic Pain Syndrome and Lower Urinary Tract Symptoms
Brief Summary: The purpose of this study is to determine whether tamsulosin and tolterodine are effective in the treatment of men with lower urinary tract symptoms and chronic prostatitis/chronic pelvic pain syndrome.
Detailed Summary: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a common disorder in urological clinics. Most of the clinically CP/CPPS are to some extent associated with storage (irritative) symptoms, such as increased frequency, urgency, and nocturia, namely many patients with CP/CPPS have overactive bladder symptoms. Alpha-blocker therapy has been advocated as a treatment modality for CP/CPPS. Some trials showed a statistically and likely clinically significant treatment effect, while other trials showed no benefit. Therefore, tamsulosin combination with tolterodine treatment for CP/CPPS may be more effective than tamsulosin single.
Sponsor: Chongqing Medical University
Current Primary Outcome: National Institutes of Health Chronic Prostatitis Symptom Index [ Time Frame: 4 months ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Peak urinary flow rate [ Time Frame: 4 months ]
- International Index of Erectile Function [ Time Frame: 4 months ]
Original Secondary Outcome: Same as current
Information By: Chongqing Medical University
Dates:
Date Received: June 3, 2009
Date Started: August 2009
Date Completion: January 2010
Last Updated: June 4, 2009
Last Verified: June 2009
