Clinical Trial: Insulin Resistance in Women With Prolactinoma

Study Status: Completed
Recruit Status: Completed
Study Type: Observational

Official Title: Insulin Resistance and Lipid Profile in Non-Obese Women With Prolactinoma Treated With Dopamine Agonists

Brief Summary:

Prolactin is suggested to influence insulin resistance, but scarce data is available on the metabolic profile of patients with prolactinoma.

The purpose of the protocol was to evaluate cardiovascular disease risk factors in women with prolactinoma treated with dopamine agonists and to study the influence of disease control and anthropometry on their metabolic profile.

Detailed Summary: A cross-sectional study was performed in non-obese premenopausal women with prolactinoma treated with dopamine agonists evaluated regarding glucose, insulin, Homeostasis Model Assessment (HOMA), lipid profile, C reactive protein (CRP), body mass index (BMI), waist circumference, prolactin, estradiol, testosterone, and sex hormone binding globulin (SHBG). They were compared with control women of similar age and BMI distribution.
Sponsor: Universidade Federal do Rio de Janeiro

Current Primary Outcome:

Original Primary Outcome:

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Universidade Federal do Rio de Janeiro

Dates:
Date Received: May 30, 2007
Date Started: October 2004
Date Completion:
Last Updated: May 30, 2007
Last Verified: April 2007