Clinical Trial: Antibiotics for Postpartum Third and Fourth Degree Perineal Tear Repairs
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: A Randomized Controlled Trial of the Effect of Prophylactic Antibiotics on the Infection Rate in Postpartum Third and Fourth Degree Perineal Tear Repairs
Brief Summary: This study is undertaken to find out whether prophylactic antibiotics can decrease the infection rate in third and fourth degree perineal tear repairs done in the immediate postpartum period.
Detailed Summary: After obtaining consent patients who sustained third or fourth degree perineal laceration after vaginal delivery were randomly assigned to a single dose of antibiotic (cefotetan or cefoxitin, 1 g intravenously or clindamycin, 900 mg intravenously, if allergic to penicillin), or placebo (100ml normal saline) intravenously.
Sponsor: Stanford University
Current Primary Outcome: No perineal breakdown or infection [ Time Frame: Six weeks post partum ]
Original Primary Outcome: No perineal breakdown or infection
Current Secondary Outcome:
Original Secondary Outcome:
Information By: Stanford University
Dates:
Date Received: September 13, 2005
Date Started: September 2003
Date Completion:
Last Updated: June 13, 2011
Last Verified: June 2011