Clinical Trial: Hypokalemia and Intravenous Patient Controlled Analgesia
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: Hypokalemia and Intravenous Patient Controlled Analgesia
Brief Summary: The increase in stress hormone level and hyperventilation caused by the postoperative pain may contribute to the development of hypokalemia during postoperative period. Therefore, if the postoperative pain is well controlled by the IV-PCA,the plasma potassium level during the postoperative period may be not affected by stress response. The researchers tried to investigate the effect of IV-PCA on potassium regulation during the postoperative period.
Detailed Summary:
Intravenous patient controlled analgesia(IV-PCA) has been widely used to control postoperative pain. The increase in stress hormone level and hyperventilation caused by the postoperative pain may contribute to the development of hypokalemia during postoperative period. Hypokalemia is a risk factor for postoperative arrhythmia. Therefore, if the postoperative pain is well controlled by the IV-PCA, the plasma potassium level during the postoperative period may be not affected by stress response, and the incidence of hypokalemia may be reduced. The researchers tried to investigate the effect of IV-PCA on potassium regulation during the postoperative period.
The researchers divided the patients undergoing laparoscopic cholecystectomy into two groups of IV-PCA group and control group. The researchers compared the plasma potassium concentration from the preoperative to postoperative period.
Sponsor: Seoul Medical Center
Current Primary Outcome: plasma potassium concentration [ Time Frame: one day interval (average) ]
blood sample for electrolyte including plasma potassium concentration checking six times
; at outpatient department (T1), at 08:00 A.M. of the day of surgery (T2), one hour after the end of surgery (T3), at 8:00 A.M. of first (T4), second (T5), and third postoperative day (T6)
Original Primary Outcome: Same as current
Current Secondary Outcome: Visual Analogue Scale (VAS) score [ Time Frame: one day interval (average) ]
patient-reported VAS score during postoperative period checking fourtimes
; one hour after the end of surgery (T3), at 8:00 A.M. of first (T4), second (T5), and third postoperative day (T6)
Original Secondary Outcome: Same as current
Information By: Seoul Medical Center
Dates:
Date Received: December 30, 2010
Date Started: January 2010
Date Completion:
Last Updated: January 3, 2011
Last Verified: December 2010
