Clinical Trial: Dexamethasone for Postoperative Nausea and Vomiting

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Optimizing Anesthesia Antiemetic Measures Versus Combination With Dexamethasone or Ondansetron in the Prevention of Postoperative Nausea and Vomiting.

Brief Summary: The investigators want to test the efficacy of these anesthetic antiemetic measures collectively with or without ondansetron or dexamethasone, in the prevention of postoperative nausea and vomiting (PONV) in patients undergoing laparoscopic cholecystectomy.

Detailed Summary:

More than half of the patients undergoing laparoscopic cholecystectomy will have postoperative nausea and vomiting (PONV). PONV is related to surgical, anesthetic and patient factors.

We want to test the efficacy of these anesthetic antiemetic measures collectively with or without ondansetron or dexamethasone, in the prevention of PONV in patients undergoing laparoscopic cholecystectomy.

Three groups to be studied : (Group O) will receive 4 mg ondansetron, (Group D) will receive 8 mg dexamethasone and (Group P) will receive normal saline .

Sponsor: University of Jordan

Current Primary Outcome: incidence of nausea and vomiting in each of the three studied groups. [ Time Frame: 5 months ]

Original Primary Outcome: Same as current

Current Secondary Outcome: Assess the postoperative Visual Analog Score for pain assessment in each of the three studied groups [ Time Frame: 5 months ]

Original Secondary Outcome: Same as current

Information By: University of Jordan

Dates:
Date Received: January 15, 2009
Date Started: November 2007
Date Completion:
Last Updated: May 12, 2016
Last Verified: May 2016