Clinical Trial: A New Method for Estimating Dynamic Intrinsic PEEP
Study Status: Completed
Recruit Status: Completed
Study Type: Observational
Official Title: A New Method for Estimating Dynamic Positive End-expiratory Pressure. Description and Validation With PEEPi Dyn Measured With Transdiaphragmatic Pressure
Brief Summary: Dinamic intrinsic PEEP is
Detailed Summary:
Dynamic intrinsic positive end-expiratory pressure (PEEPi dyn) play an important pathophysiology role in many acute respiratory pathologies.
The most accurate method to quantify PEEPi dyn is to measure the rise in transdiaphragmatic pressure (Pdi) at end expiration at the point of the contraction of the inspiratory muscles until inspiratory flow starts.
Such method, however, is invasive, poor comfortable and require patient active collaboration.
The purpose of this study is describe a new non-invasive method for estimate PEEPi dyn and validate this method with gold-standard-one.
Sponsor: Azienda Ospedaliera Universitaria di Bologna Policlinico S. Orsola Malpighi
Current Primary Outcome: Correlation and agreement between AutoPEEP recorded with the transdiaphragmatic pressure (Pdi) vs ecography measurements. [ Time Frame: 20 minutes ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Correlation and agreement between neural inspiratory time and ecographic inspiratory time [ Time Frame: 10 minutes ]
- Inter-rater agreement to assest method reliability [ Time Frame: 10 minutes ]
Original Secondary Outcome: Same as current
Information By: Azienda Ospedaliera Universitaria di Bologna Policlinico S. Orsola Malpighi
Dates:
Date Received: March 9, 2015
Date Started: April 2015
Date Completion:
Last Updated: December 28, 2015
Last Verified: August 2015
