Clinical Trial: Metabolic Disturbances in Polycystic Ovary Syndrome (PCOS)

Study Status: Completed
Recruit Status: Completed
Study Type: Observational

Official Title: Insulin Resistance in Polycystic Ovary Syndrome (PCOS)

Brief Summary: The scope of the study was to investigate different metabolic aspects that may lead to or are a consequence of insulin resistance in premenopausal women with polycystic ovary syndrome (PCOS). We use gold standard methods for evaluation of insulin resistance. We take muscle and fat biopsies for investigation of gene expression of different cytokines associated with insulin resistance. We investigate the incretin hormones GIP and GLP-1. These two hormones play a central role in glycemic control, and diabetic subjects are known to have alterations in their incretin hormones. The incretin hormones have not previously been investigated in women with PCOS.

Detailed Summary:
Sponsor: Hvidovre University Hospital

Current Primary Outcome: insulin resistance [ Time Frame: 2004-2006 ]

Original Primary Outcome: Same as current

Current Secondary Outcome: gene expression of cytokines in fatty tissue [ Time Frame: 2004-2006 ]

Original Secondary Outcome: Same as current

Information By: Hvidovre University Hospital

Dates:
Date Received: January 17, 2008
Date Started: February 2004
Date Completion:
Last Updated: February 1, 2008
Last Verified: January 2008