Clinical Trial: The Influence of Pneumoperitoneum on Minimal Invasive Cardiac Output Measurements

Study Status: Terminated
Recruit Status: Terminated
Study Type: Interventional

Official Title: The Influence of Pneumoperitoneum on Minimal Invasive Cardiac Output Measurements

Brief Summary: Perioperative goal directed fluid therapy may reduce complication rate after surgery. Minimal invasive cardiac output monitoring is a key method to guide fluid therapy. More operations are being performed by keyhole surgery (laparoscopy). For laparoscopy, the abdomen is filled with carbon dioxide. Increased pressure in the abdomen may influence minimal cardiac output monitoring, therefore minimal cardiac output monitoring is not recommended during laparoscopy. This study aims to validate minimal cardiac output monitoring during laparoscopy and therefore facilitate for goal directed fluid therapy.

Detailed Summary:
Sponsor: Haukeland University Hospital

Current Primary Outcome: Change of stroke volume variation and pulse pressure variation during pneumoperitoneum [ Time Frame: peroperative ]

Change in PPV/SVV(LiDCO), PPV(Philips) and SVV/CO(TEE) in percent before and after pneumoperitoneum.


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Difference in measurements from different methods of minimal cardiac output monitoring. [ Time Frame: peroperative ]
  • Effect of fluid bolus under pneumoperitoneum (responder vs. non-responder) [ Time Frame: peroperative ]


Original Secondary Outcome: Same as current

Information By: Haukeland University Hospital

Dates:
Date Received: May 13, 2013
Date Started: May 2013
Date Completion:
Last Updated: January 21, 2016
Last Verified: January 2016