Clinical Trial: Effects and Safety of Caspofungin and Corticosteroids in Pneumocystis Pneumonia in Non-HIV Patients

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional

Official Title:

Brief Summary: Pneumocystis Pneumonia is increasing in Immunocompromised Non-HIV Infected Patients. The effects and safety of caspofungin and corticosteroids is not certain in this population. All Immunocompromised Non-HIV patients with respiratory failure were randomized into caspofungin and non-caspofungin group and corticosteroids and non-steroids group. The major outcome is 28 day mortality, the second outcome are time of respiratory rate decreases to less than 25 breath per minute, body temperature lower than 37.3℃.

Detailed Summary:
Sponsor: Beijing Chao Yang Hospital

Current Primary Outcome: mortality [ Time Frame: 28 days ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

• Time for release of fever [ Time Frame: 2 days ]
  Time for body temperature less than 37.3℃ for 48 hours
• Time for release of respiratory distress [ Time Frame: 2 days ]
  Time for respiratory rate <25 breathes per minute for 48 hours

Original Secondary Outcome: Same as current

Information By: Beijing Chao Yang Hospital

Dates:
Date Received: November 8, 2015
Date Started: November 2015
Date Completion:
Last Updated: November 10, 2015
Last Verified: November 2015