Clinical Trial: Corticosteroids in the Treatment of Tuberculous Pleurisy
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: A Multicenter, Placebo-Controlled, Double-Blind, Randomized Clinical Trial to Evaluate the Efficacy and Safety of Corticosteroids for Treatment of Patients With Tuberculous Pleur
Brief Summary: Tuberculous pleurisy is associated with inflammation and fibrosis. Adjunctive corticosteroids are used for tuberculous pleurisy because their anti-inflammatory effect is thought to minimise pleural reactivity and thereby reduce residual pleural thickening. The purpose is to evaluate the efficacy and safety of oral prednisolone for treatment of adult patients with tuberculous pleurisy.
Detailed Summary:
Sponsor: Guangxi Medical University
Current Primary Outcome:
- Death
- Presence of pleural thickening
- Pulmonary function at completion of treatment
- Adverse drug effects
Original Primary Outcome: Same as current
Current Secondary Outcome:
- Improvement in clinical symptoms and signs (such as pleuritic chest pain, temperature)
- Reabsorption of pleural effusion
- Failure rate at the end of treatment
Original Secondary Outcome: Same as current
Information By: Guangxi Medical University
Dates:
Date Received: June 19, 2006
Date Started: July 2006
Date Completion:
Last Updated: August 25, 2008
Last Verified: August 2008
