Clinical Trial: Effects of Pleural Effusion Drainage on Respiratory System Mechanics

Study Status: Recruiting
Recruit Status: Unknown status
Study Type: Observational

Official Title: Effects of Pleural Effusion Drainage on Respiratory System Mechanics in Mechanically Ventilated Patients, as Measured by Esophageal Balloon.

Brief Summary: The effects of pleural drainage on lung mechanics are unknown. Insertion of esophageal balloon will allow us to measure and assess pleural pressure, and thus assess any possible effects of pleural fluid drainage may have on lung mechanics.

Detailed Summary: Esophageal balloon will be inserted prior to pleural fluid drainage.
Sponsor: Wolfson Medical Center

Current Primary Outcome: chest wall and lung compliance [ Time Frame: 1 year ]

The use of esophageal balloon allows us to partition respiratory system into its components, namely, chest wall and lung compliance. These measurements have not been described so far in patients undergoing pleural fluid drainage. Thus, assessment of esophageal pressure which is a surrogate of pleural pressure will allow us an accurate measurement of the effect of pleural fluid drainage on chest wall and lung mechanics.


Original Primary Outcome: Same as current

Current Secondary Outcome: oxygenation [ Time Frame: 1 year ]

We suspect that pleural fluid drainage will be associated with improved chest wall and lung mechanics. If this will be the case, then we expect a concomitant improvement in oxygenation.


Original Secondary Outcome: Same as current

Information By: Wolfson Medical Center

Dates:
Date Received: July 23, 2012
Date Started: July 2012
Date Completion: July 2013
Last Updated: July 25, 2012
Last Verified: July 2012