Clinical Trial: Efficacy Study of Random Placenta Margin Incision to Treat Complete Placenta Previa

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional

Official Title: Random Placenta Margin Incision for Hemorrhage Control During Cesarean Section of Complete Placenta Previa Pregnancies

Brief Summary: The purpose of this study is to assess the efficacy of random placenta margin incision for hemorrhage control during cesarean section of complete placenta previa pregnancies.

Detailed Summary:

Placenta previa is used to describe a placenta that is implanted over or very near the internal cervical os and the complete placenta previa is defined that the internal os is covered completely by placenta. This obstetric complication is associated with high risks for maternal hemorrhage and emergency peripartum hysterectomy can be the only effective action to take, although it carries many morbidities for the women especially those with low parity. Although, nowadays the obstetrician can diagnose placenta previa before delivery, it is still one of the important causes of maternal mortality. The only safe and appropriate mode of delivery for placenta previa is by cesarean delivery. In the absence of accreta, this can usually be accomplished using a lower segment uterine incision. Because of cutting through the placenta, it is often associated with increased maternal bleeding. In addition, the umbilical cord will be also excessive blood loss when the placenta is transected. Theoretically, random placenta margin incision can effectively avoid the damage of the placenta and reduce the maternal blood loss.

The investigators conduct a prospective study to assess the efficacy of random placenta margin incision for hemorrhage control during cesarean section of complete placenta previa pregnancies at Department of Obstetrics, Southern Medical University Affiliated Maternal and Child Health Hospital of Foshan, since January 2016 till December 2016, after approval of the study protocol by the Local Ethical Committee.

All participants have complete placenta previa and provide written informed consent to undergo any procedure necessary as an attempt to avoid hysterectomy. And they also provide written informed consent to undergo hysterectomy if all measures attempted to preserve the uterus fail.

Same as current

Current Secondary Outcome:

  • Number of blood products transfused [ Time Frame: within the first 30 days after cesarean section ]
  • Length of hospitalization [ Time Frame: 6 months after delivery ]


Original Secondary Outcome: Same as current

Information By: Maternal and Child Health Hospital of Foshan

Dates:
Date Received: February 22, 2016
Date Started: January 2016
Date Completion: June 2017
Last Updated: March 21, 2017
Last Verified: March 2017