Clinical Trial: Skin Imaging With Technologies in Development

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational

Official Title: Non-invasive Imaging Modalities for Assessment of Normal and Lesional Skin

Brief Summary: The purpose of this research is to develop non-invasive imaging modalities for assessment of skin. This is a pilot study which will use multiple imaging modalities to collect information on normal and lesional skin. The researchers understand that the purpose of this study is not to evaluate any particular treatment and an investigation of a new therapeutic intervention would require an additional protocol. Skin conditions to be studied include vascular lesions, pigmentary disorders, inflammatory conditions and neoplasms.

Detailed Summary:

Normal and lesional skin will be assessed by the following imaging modalities:

  1. Laser Speckle Imaging can provide information about relative blood flow in a tissue. In skin it can be used to determine what areas have more blood flow and whether a particular intervention or treatment affects blood flow.
  2. Optical Coherence Tomography and Optical Doppler Tomography can provide pictures of blood vessels in an area of the body and can also tell how fast blood is flowing in that area.
  3. Photon Migration Spectroscopy can provide information about the amount of blood, oxygen, fat and water is in a tissue.
  4. Multi-Spectral Imaging can provide a 3 dimensional image of structures within the skin.
  5. Multiphoton Microscopy can provide images of structures of the skin.

Sponsor: University of California, Irvine

Current Primary Outcome: Collect information on normal and lesional skin [ Time Frame: up to 12 weeks ]

Develop non-invasive imaging modalities for assessment of skin.


Original Primary Outcome: Learn information about the human skin which could be useful for diagnosis or guiding treatment. [ Time Frame: 4 weeks ]

Current Secondary Outcome:

Original Secondary Outcome:

Information By: University of California, Irvine

Dates:
Date Received: September 30, 2008
Date Started: October 2008
Date Completion: October 2018
Last Updated: February 8, 2017
Last Verified: February 2017