Clinical Trial: The Cancer of the Pancreas Screening-5 CAPS5)Study

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational

Official Title: The Cancer of the Pancreas Screening-5 CAPS5)Study

Brief Summary: Johns Hopkins clinical research office quality assurance group will monitor and audit this study at Johns Hopkins. The Sub Investigator at each site will be responsible for internal monitoring at their site.

Detailed Summary: The Sub Investigator at each site will be responsible for internal monitoring at their site. The site sub Investigator and study team will report any serious adverse events to Principal Investigator and annually report adverse events.
Sponsor: Johns Hopkins University

Current Primary Outcome: Evaluate pancreatic juice for early cancer markers. [ Time Frame: 8 years ]

Aim #1: To evaluate pancreatic fluid mutations and circulating pancreatic epithelial cells as accurate markers of neoplasia by comparing their prevalence in cases with sporadic pancreatic neoplasia to healthy and disease controls.


Original Primary Outcome: Same as current

Current Secondary Outcome: Compare pancreas juice with pancreas cyst fluid [ Time Frame: 8 years ]

Aim #2: To compare the prevalence of pancreatic fluid mutations and circulating pancreatic epithelial cells among a prospective cohort of individuals with sporadic pancreatic cysts undergoing pancreatic surveillance.


Original Secondary Outcome: Same as current

Information By: Johns Hopkins University

Dates:
Date Received: November 26, 2013
Date Started: January 2014
Date Completion: December 2023
Last Updated: March 13, 2017
Last Verified: March 2017