Clinical Trial: Bacterial Overgrowth Associated With Chronic Multisymptom Illness Complex
Study Status: Completed
Recruit Status: Unknown status
Study Type: Interventional
Official Title: Bacterial Overgrowth Associated With Chronic Multisymptom Illness Complex
Brief Summary: The adverse impact of Gulf War Syndrome (GWS) on the health of veterans and on the resources of the VA Healthcare System underscores the need to resolve its underlying cause. In response, the investigators propose to investigate the central hypothesis that gut bacteria may be responsible for symptoms associated with GWS. The investigators will enroll a total of 120 patients with GWS and 90 healthy controls.
Detailed Summary: The investigator will assess the prevalence and role of abnormal gut microbial fermentation among Veterans with GWS and investigate the efficacy of diagnostic and treatment strategies directed at indigenous gut microbes in the management of GWS.
Sponsor: Henry C. Lin, MD
Current Primary Outcome:
- To compare the pattern of bacterial gas excretion in breath among Veterans with Gulf War Syndrome vs. Controls using Lactulose Breath Test [ Time Frame: every 15 minutes for 180 minutes ]
- To determine the response to antibiotic treatment in Gulf War Syndrome patients. [ Time Frame: Two weeks ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
Original Secondary Outcome:
Information By: New Mexico VA Healthcare System
Dates:
Date Received: August 10, 2009
Date Started: April 2009
Date Completion:
Last Updated: April 30, 2013
Last Verified: April 2013
