Clinical Trial: Biomarkers in Urine Samples From Patients With Wilms Tumor

Study Status: Completed
Recruit Status: Completed
Study Type: Observational

Official Title: Discovery and Validation of Wilms Tumor Markers Using Urine Proteomics

Brief Summary:

RATIONALE: Studying samples of urine from patients with cancer in the laboratory may help doctors identify biomarkers related to cancer.

PURPOSE: This clinical trial studies biomarkers in urine from patients with Wilms tumor.

Detailed Summary:

OBJECTIVES:

• To validate the prognostic performance of specific-candidate Wilms tumor markers by measuring their urinary concentration using enzyme-linked immunosorbent assays (ELISAs) in urine specimens collected at diagnosis from 50 patients with favorable histology Wilms tumor who relapsed and 50 patients who did not relapse.

OUTLINE: Urine specimens are analyzed using enzyme-linked immunosorbent assays (ELISAs) for biomarkers.

Sponsor: Children's Oncology Group

Current Primary Outcome: Wilms tumor biomarkers identified by ELISA

Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Children's Oncology Group

Dates:
Date Received: March 6, 2012
Date Started: March 2012
Date Completion:
Last Updated: July 7, 2016
Last Verified: July 2016