Clinical Trial: Spironolactone and Prevention of Peritoneal Fibrosis in Peritoneal Dialysis
Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: Role of Renin Angiotensin Blockade in Peritoneal Fibrosis in Peritoneal Dialysis Patients
Brief Summary: This is a double blind randomized controlled study to evaluate the effect of aldactone on peritoneal fibrosis on incident peritoneal dialysis patients. The study would include a total of 40 incident peritoneal dialysis patients. Peritoneal biopsy would be made at randomization and 6 months after the intervention to evaluate the effect of renin angiotensin blockade on peritoneal fibrosis.
Detailed Summary:
Sponsor: Instituto Nacional de Cardiologia Ignacio Chavez
Current Primary Outcome: Peritoneal fibrosis [ Time Frame: 6 months ]
Original Primary Outcome: Same as current
Current Secondary Outcome:
Original Secondary Outcome:
Information By: Instituto Nacional de Cardiologia Ignacio Chavez
Dates:
Date Received: March 17, 2009
Date Started: July 2008
Date Completion:
Last Updated: October 23, 2012
Last Verified: March 2009