Clinical Trial: Comparison of Volume Controlled Ventilation and Autoflow-volume Controlled Ventilation in Robot-assisted Laparoscopic Radical Prostatectomy With Steep Trendelenburg Position and Pneumoperitoneum

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title:

Brief Summary: The steep trendelenburg position and pneumoperitoneum during laparoscopic surgery have the potential to cause an adverse effects on respiratory mechanics and gas exchange. Autoflow-volume controlled ventilation may improve lung compliance and reduce airway peak pressure. Therefore, the aim of this study is to evaluate whether Autoflow-volume controlled ventilation improves gas exchange and respiratory mechanics in patients undergoing robot-assisted laparoscopic radical prostatectomy.

Detailed Summary:
Sponsor: Yonsei University

Current Primary Outcome: arterial oxygen tension (PaO2) [ Time Frame: 30 minutes after steep trendelenburg position and pneumoperitoneum. ]

Arterial oxygen tension (PaO2) obtained from arterial blood gas analysis


Original Primary Outcome: Same as current

Current Secondary Outcome: The peak inspiratory pressure [ Time Frame: 10 minutes after anesthesia induction, 30 and 60 minutes after steep trendelenburg position and pneumoperitoneum, and 10 minutes after supine position and CO2 desufflation. ]

The peak inspiratory pressure during mechanical ventilation with endotracheal intubation under general anesthesia


Original Secondary Outcome: Same as current

Information By: Yonsei University

Dates:
Date Received: June 9, 2016
Date Started: June 2016
Date Completion:
Last Updated: December 25, 2016
Last Verified: December 2016