Clinical Trial: Pneumoperitoneum and Gynecological Laparoscopic Surgery: An Observational Clinical Study

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Observational

Official Title: Impact Of Posture and Prolonged Pneumoperitoneum on Intra-Operative and Postoperative Outcomes During Gynecological Laparoscopic Surgery: An Observational Clinical Study

Brief Summary: Laparoscopic surgery is now widely established.Laparoscopic surgery involves insufflation of a gas (usually carbon dioxide) into the peritoneal cavity producing a pneumoperitoneum. The raised intra-abdominal pressure of the pneumoperitoneum, alteration in the patient's position and effects of carbon dioxide absorption cause changes in physiology, especially within the cardiovascular and respiratory systems.

Detailed Summary: The study will be carried out after approval of the ethical committee of Faculty of Medicine, Assiut University. A full preoperative anesthetic assessment will be carried out. Particular attention to the cardiovascular and respiratory systems is essential because of potential effects of the pneumoperitoneum and patient position.
Sponsor: Assiut University

Current Primary Outcome:

  • mean arterial blood pressure [ Time Frame: within the duration of the operation ]
    mean arterial blood pressure will be monitored at different times
  • Pulmonary function tests [ Time Frame: within the first 24 hours ]
    forced expiratory volume at one second


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • PaO2 [ Time Frame: within the first 24 hours ]
    PaO2 will be monitored at different times
  • Arterial to end-tidal PaCO2- difference [ Time Frame: within the first 24 hours ]
    Arterial to end-tidal PaCO2- difference will be monitored at different times
  • Intra-abdominal pressure [ Time Frame: within the first 24 hours ]
    Intra-abdominal pressure by direct measurement and indirect by Foley´s catheter will be monitored at different times (Cm water)
  • Postoperative nausea and vomiting [ Time Frame: within the first 24 hours ]
    Postoperative nausea and vomiting will be monitored at different times by special scale
  • Analgesic requirement [ Time Frame: within the first 24 hours ]
    Analgesic requirement will be monitored at different times by special scale (VAS)


Original Secondary Outcome: Same as current

Information By: Assiut University

Dates:
Date Received: May 17, 2017
Date Started: May 2017
Date Completion: June 2018
Last Updated: May 19, 2017
Last Verified: May 2017