Clinical Trial: Impact of Debridement Invasiveness on Attachment Gain After Antiinfective Periodontal Therapy

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional

Official Title: Impact of Debridement Invasiveness on Attachment Gain After Antiinfective Periodontal Therapy

Brief Summary: This study compared the gain of periodontal attachment after concomitant one-stage removal of bacterial biofilms and subgingival calculus with a two-stage procedure removing subgingival calculus 6 weeks after the initial removal of soft subgingival bacterial biofilms.

Detailed Summary: The concomitant removal of subgingival calculus and soft bacterial biofilms in a one-stage procedure might impair periodontal healing in deep infrabony pockets due to the mechanical disruption of demineralized bone sections at the bottom of periodontal lesions. This randomized controlled clinical trial therefore aims at comparing the resulting attachment gain 6 months after one-stage antiinfective periodontal therapy comprising the concomitant subgingival removal of soft bacterial biofilms and calculus with a two-stage approach removing subgingival calculus only 6 weeks after the initial removal of soft subgingival bacterial biofilms.
Sponsor: Wuerzburg University Hospital

Current Primary Outcome: Reduction of Clinical Attachment Loss [ Time Frame: 168 days (24 weeks) ]

Measuring the distance between the cemento-enamel-junction and the probeable bottom of the periodontal pocket


Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Bleeding on Probing [ Time Frame: 168 days (24 weeks) ]
    Recording the possible appearance of a bleeding spot immediately after the probing of periodontal lesions for the measurement of clinical attachment loss
  • Probing Pocket Depth [ Time Frame: 168 days (24 weeks) ]
    Measuring the distance between the gingival sulcus and the bottom of the periodontal lesion
  • Gingival Index [ Time Frame: 168 days (24 weeks) ]
    Visual Assessment of the inflammatory status of the gingiva according to the criteria set by Lobene et al.
  • Plaque Index [ Time Frame: 168 days (24 weeks) ]
    Measuring the extent of supragingival plaque coverage according to the criteria set by Silness and Loe


Original Secondary Outcome: Same as current

Information By: Wuerzburg University Hospital

Dates:
Date Received: March 27, 2017
Date Started: June 1, 2016
Date Completion: December 1, 2017
Last Updated: March 30, 2017
Last Verified: March 2017