Clinical Trial: Impact of Colchicine Therapy on Arrhythmia Recurrence After Acute Pericardial Effusion

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional

Official Title: Impact of Colchicine Therapy on Arrhythmia Recurrence After Acute Pericardial Effusion Following Catheter Ablation of Atrial Fibrillation

Brief Summary: The effects colchicine administration for acute pericardial effusion after radiofrequency catheter ablation (RFCA) of atrial fibrillation on the recurrences of arrhythmia.

Detailed Summary: RFCA was started as a rhythm control of atrial fibrillation about 10 years before and the superiority of RFCA to medical treatment has been continuously reporting, so RFCA is globally performed nowadays. Acute pericardial effusion could occur during RFCA as complication, that might be developed to cardiac tamponade needed immediate pericardiocentesis. The inflammation developed after pericardiocentesis might be associated with the recurrences of atrial fibrillation, it could be presumed by the frequent occurrence of atrial fibrillation after open-heart surgery. The inflammation can be suppressed by administration of colchicine and the effects of colchicine have been proven to decrease the development of atrial fibrillation.
Sponsor: Yong Seog Oh

Current Primary Outcome: recurrence of atrial arrhythimia [ Time Frame: 1 year after colchicines administration ]

Original Primary Outcome: Same as current

Current Secondary Outcome: recurrence of atrial arrhythimia [ Time Frame: 3 year after colchicines administration ]

Original Secondary Outcome: Same as current

Information By: Seoul St. Mary's Hospital

Dates:
Date Received: October 5, 2014
Date Started: July 2014
Date Completion: November 2018
Last Updated: April 24, 2017
Last Verified: April 2017