Clinical Trial: Amitriptyline Regarding Nimesulide in Acute Idiopathic Adhesive Capsulitis

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Comparative Study Between Amitriptyline Regarding Nimesulide Associated to Nervous Blockade in the Acute Treatment of Idiopathic Adhesive Capsulitis

Brief Summary: The adhesive capsulitis is a disease of the shoulder characterized by pain and limitation of movement amplitude. It is defined as for etiology, having discordant theories that related it to an inflammatory condition or to an algoneurodystrophy process. There is not yet a consensus about the best option of treatment. The non-steroidal anti-inflammatories have analgesic and anti-inflammatory activity, where the mechanism of action is the inhibition of prostaglandin synthesis. The antidepressants have been increasingly used in the control of chronic pain and the major action mechanism to have the analgesic effect seems to be based on inhibition of neurotransmitters reuptake noradrenaline and/or serotonin) in nerve cell endings. Literature studies associate the practice of the nerve suprascapular blockade with anaesthetics to good results of clinical improvement of the pain, however, so far, no clinical studies comparing the efficacy of the non-steroidal antiinflammatories or tricyclic antidepressants to nervous blockage were registered in the acute treatment of adhesive capsulitis.

Detailed Summary:
Sponsor: Universidade do Sul de Santa Catarina

Current Primary Outcome: Pain and disability of the shoulder [ Time Frame: Days 0 and 14 after treatment begining ]

Pain and disability of the shoulder, measured by the use of SPADI questionnaire.


Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Universidade do Sul de Santa Catarina

Dates:
Date Received: March 1, 2011
Date Started: February 2011
Date Completion:
Last Updated: January 27, 2012
Last Verified: September 2011