Clinical Trial: To Compare the Strategies of Universal Antibiotic Prophylaxis Versus Screen-and-treat in Reducing Infective Complications and Re-infection in Women Who Undergo Termination of Pregnancy

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: To Compare the Strategies of Universal Antibiotic Prophylaxis Versus Screen-and-treat in Reducing Infective Complications and Re-infection in Women Who Undergo Termination of Pregnancy

Brief Summary: Screen-and-treat approach reduces postabortal pelvic inflammatory disease after induced abortion, and at the same time alters women's sexual behavior and prevents further re-infection by sexually transmitted infections when compared to the universal antibiotic prophylaxis strategy.

Detailed Summary: While universal antibiotic prophylaxis during induced abortion has been proven to reduce postabortal pelvic inflammatory diseases, screen-and-treat approach has the potential benefit of altering women's sexual behavior and preventing further re-infection by sexually transmitted infections. We conducted a randomized controlled trial to compare the effect of the two approaches in preventing postabortal pelvic inflammatory disease and the women's sexual behavior.
Sponsor: The University of Hong Kong

Current Primary Outcome: Rate of postabortal inflammatory disease 6 weeks after induced abortion. [ Time Frame: 6 weeks after induced abortion. ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

  • Rate of re-infection by sexually transmitted infections 24 weeks after induced abortion. [ Time Frame: 24 weeks after induced abortion. ]
  • Proportion of women having abstinence from sexual intercourse or using condom at 6 weeks, 24 weeks and 1 year after induced abortion. [ Time Frame: 6 weeks, 24 weeks and 1 year after induced abortion ]


Original Secondary Outcome: Same as current

Information By: The University of Hong Kong

Dates:
Date Received: April 21, 2013
Date Started: September 1999
Date Completion:
Last Updated: April 24, 2013
Last Verified: April 2013