Clinical Trial: Adherence in Pediatric Multiple Sclerosis

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Treatment Adherence in Pediatric Multiple Sclerosis

Brief Summary: Disease modifying therapies (DMT) are widely used for children and adolescents with MS. Nonetheless, many pediatric patients continue to relapse and therefore require changes in therapy. We designed this research study to learn more about medication use in children and adolescents with MS. We are also interested in learning what a behavioral feedback intervention can tell us about adherence to medicine. Finally, we hope this research project will inform the way we provide clinical care for children and adolescents with MS.

Detailed Summary:
Sponsor: The Hospital for Sick Children

Current Primary Outcome: Adherence [ Time Frame: baseline to three months & three months to six months ]

Adherence will be estimated pre- and post-intervention by computing the proportion of missed doses to expected doses from baseline to three months (i.e. pre-intervention) and three months to six months (i.e. post-intervention).


Original Primary Outcome: Same as current

Current Secondary Outcome: Self-Efficacy [ Time Frame: baseline, three months, and six months ]

Self-efficacy scores (MS Self-Efficacy Measure) will be compared at baseline, three months, and six months between the two study arms.


Original Secondary Outcome: Same as current

Information By: The Hospital for Sick Children

Dates:
Date Received: September 5, 2014
Date Started: January 2013
Date Completion:
Last Updated: September 19, 2016
Last Verified: September 2016