Clinical Trial: Molecular Assessment of Artemisinin Resistance Markers in Eastern and Western Border Areas of Myanmar

Study Status: Completed
Recruit Status: Completed
Study Type: Observational

Official Title: Molecular Assessment of Artemisinin Resistance Markers, K13 Kelch Propeller and Multi-drug Resistant Gene Polymorphism in Eastern and Western Border Areas of Myanmar

Brief Summary:

  • Artemisinin resistance have been documented in Myanmar and Myanmar artemisinin resistance containment measures have been launched since 2009-2010.
  • It is important to monitor the spread and magnitude of artemisinin resistant malaria in Myanmar.
  • So, day-3 surveillance study have been conducted.
  • Recently artemisinin resistant molecular marker, K13 have been identified and it was used as a tool in this study.

Detailed Summary:
Sponsor: Myat Htut Nyunt

Current Primary Outcome: day-3 parasite positivity [ Time Frame: 3 days ]

All of the enrolled patients were monitored with appropriate care up to third day and take the samples on day-3.


Original Primary Outcome: Same as current

Current Secondary Outcome: Prevalence of the drug resistance marker [ Time Frame: up to day-3 ]

By using the dried blood spots, drug resistance markers were detected by molecular method.


Original Secondary Outcome: Same as current

Information By: Department of Medical Research, Lower Myanmar

Dates:
Date Received: July 22, 2014
Date Started: July 2013
Date Completion:
Last Updated: July 22, 2014
Last Verified: July 2014