Clinical Trial: Prolensa (Bromfenac) 0.07% QD vs. Ilevro (Nepafenac) 0.3% QD for Treatment of Ocular Inflammation Post Cataract Surgery

Study Status: Recruiting
Recruit Status: Recruiting
Study Type: Interventional

Official Title: Clinical Outcomes of Prolensa (Bromfenac Ophthalmic Solution) 0.07% QD vs. Ilevro (Nepafenac Ophthalmic Suspension) 0.3% QD for Treatment of Ocular Inflammation Associated With Cataract Surgery

Brief Summary: To investigate inflammation, visual acuity and macular thickness after treatment with Prolensa vs Ilevro after cataract surgery.

Detailed Summary: To investigate the clinical outcomes for inflammation, visual acuity and macular thickness after treatment with Prolensa (bromfenac ophthalmic solution) 0.07% QD in subjects who have undergone cataract extraction with posterior chamber intraocular lens implantation.
Sponsor: Melissa Toyos, MD

Current Primary Outcome: Treatment of inflammation associated with cataract surgery [ Time Frame: 42 days +/-7 days ]

To investigate the clinical outcomes for inflammation after treatment with Prolensa (bromfenac ophthalmic solution) 0.07% QD in subjects who have undergone cataract extraction with posterior chamber intraocular lens implantation. Biomicroscopy with slit lamp beam of 0.3 mm in width and 1.0 mm in height will be used to determine anterior cell and flare scores at each study visit.


Original Primary Outcome: Treatment of inflammation associated with cataract surgery [ Time Frame: Up to tweny-six days ]

To investigate the clinical outcomes for inflammation after treatment with Prolensa (bromfenac ophthalmic solution) 0.07% QD in subjects who have undergone cataract extraction with posterior chamber intraocular lens implantation. Biomicroscopy with slit lamp beam of 0.3 mm in width and 1.0 mm in height will be used to determine anterior cell and flare scores at each study visit.


Current Secondary Outcome: Visual Acuity [ Time Frame: 42 days +/-7 days ]

Change in ETDRS log MAR Visual Acuity


Original Secondary Outcome: Visual Acuity [ Time Frame: End of Study ]

Change in ETDRS log MAR Visual Acuity


Information By: Discover Vision Centers

Dates:
Date Received: April 16, 2013
Date Started: April 2013
Date Completion: December 2015
Last Updated: June 10, 2015
Last Verified: June 2015