Clinical Trial: Psychodynamic Therapy for Treating Panic Disorder

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Randomized Controlled Trial of Psychodynamic Psychotherapy vs. Applied Relaxation for Panic Disorder

Brief Summary: This study will determine the effectiveness of a manualized form of brief psychodynamic psychotherapy in comparison with applied relaxation training in treating adults with panic disorder.

Detailed Summary:

This is a randomized controlled trial of a manualized form of brief psychodynamic psychotherapy in comparison with applied relaxation training, a less active form of treatment in other studies, for adults with primary Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) panic disorder.

Forty nine patients who have signed written consent who have primary DSM-IV panic disorder have been entered into the study. Randomization has been stratified by presence of major depression and use of psychoactive, anti-panic medications. Medications, if present, have been held constant. All patients have received 24 sessions of either psychodynamic psychotherapy, or applied relaxation training for panic disorder. This study is currently closed for recruitment, although final follow-up assessments have yet to be completed.


Sponsor: Weill Medical College of Cornell University

Current Primary Outcome: PDSS (panic disorder severity scale) [ Time Frame: termination, 2, 4, 6, 12 month f/u ]

Original Primary Outcome: PDSS (panic disorder severity scale)

Current Secondary Outcome:

  • SDS (Sheehan disability scale) [ Time Frame: termination, 2, 4, 6, 12 month f/u ]
  • HARS (Hamilton anxiety rating scale) [ Time Frame: termination, 2, 4, 6, 12 month f/u ]
  • HDRS (Hamilton depression rating scale) [ Time Frame: termination, 2, 4, 6, 12 month f/u ]


Original Secondary Outcome:

  • SDS (Sheehan disability scale)
  • HARS (Hamilton anxiety rating scale)
  • HDRS (Hamilton depression rating scale)


Information By: Weill Medical College of Cornell University

Dates:
Date Received: August 5, 2005
Date Started: February 2000
Date Completion:
Last Updated: June 26, 2013
Last Verified: June 2013