Clinical Trial: Biomarkers for Angiogenesis in Renal Cell Carcinoma and Neuro-endocrine Tumours.

Study Status: Completed
Recruit Status: Completed
Study Type: Observational

Official Title: Biomarkers for Angiogenesis in Renal Cell Carcinoma and Neuro-endocrine Tumours.

Brief Summary: The primary objective of this study is to analyse the concentration dopamine and serotonin in thrombocytes of patients with renal cell carcinoma and neuro-endocrine tumours compared to the concentrations of these catecholamines in healthy volunteers. The concentration dopamine and serotonin in thrombocytes with and without medication will also be evaluated.

Detailed Summary:

  • To analyse the concentration catecholamines in thrombocytes of patients with clear cell renal cell carcinoma and low grade neuroendocrine tumours.
  • To compare these concentrations with the concentrations catecholamines in thrombocytes of healthy controls.
  • To analyse the concentration catecholamines in thrombocytes of patients with clear cell renal cell carcinoma and patients with low grade neuroendocrine tumours with and without medication.

Sponsor: University Medical Center Groningen

Current Primary Outcome: Difference in concentrations DA and 5-HT in thrombocytes of patients with clear cell renal cell carcinoma and healthy controls, and patients with low grade neuroendocrine tumours and healthy controls. [ Time Frame: one year ]

Original Primary Outcome: Same as current

Current Secondary Outcome: Difference in concentrations DA and 5-HT in thrombocytes of patients with clear cell renal cell carcinoma and low grade neuroendocrine tumours with and without medication. [ Time Frame: one year ]

Original Secondary Outcome: Same as current

Information By: University Medical Center Groningen

Dates:
Date Received: July 19, 2011
Date Started: July 2011
Date Completion:
Last Updated: May 7, 2012
Last Verified: May 2012