Clinical Trial: Wait and See Antibiotic Prescription for Acute Otitis Media: A Randomized Controlled Trial

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional

Official Title: Wait and See Antibiotic Prescription for Acute Otitis Media: A Randomized Controlled Trial

Brief Summary: To determine if a wait and see prescription for ear infections in childhood reduces use of antibiotics compared to an immediate prescription

Detailed Summary: We conducted a randomized, controlled trial evaluating a consecutive series of children diagnosed with AOM during a one year period in an urban pediatric emergency department, utilizing diagnostic recommendations from contemporary evidence-based guidelines. The objectives of the study were to determine whether treatment of AOM using a “Wait and See Prescription” (WASP) significantly reduces use of antimicrobials compared with a “Standard Prescription” (SP) and to evaluate the effects of this intervention on clinical symptoms and adverse outcomes related to antibiotic use.
Sponsor: Yale University

Current Primary Outcome: Proportion of each group that filled the antibiotic prescription

Original Primary Outcome: Same as current

Current Secondary Outcome: Clinical course of the illness; side effects of medications; days of school/work missed; unscheduled medical visits

Original Secondary Outcome: Same as current

Information By: Yale University

Dates:
Date Received: November 7, 2005
Date Started: July 2004
Date Completion: August 2005
Last Updated: November 29, 2006
Last Verified: November 2005