Clinical Trial: Study on the microRNA Expression Level in Postmenopausal Osteoporosis

Study Status: Completed
Recruit Status: Unknown status
Study Type: Observational [Patient Registry]

Official Title: Study on the Molecular Mechanism in Postmenopausal Osteoporosis With Kidney Yin Deficiency Syndrome Based on miRNA Mediated Gene Translation Regulation Function by Targeti

Brief Summary: The miRNA plays an important regulation role in gene expression, and also closely related to bone metabolism. Previous research found that postmenopausal osteoporosis with kidney Yin deficiency syndrome (POP) is associated with CLCF1 gene. This project proposed by bioinformatics prediction CLCF1 targeted regulation of miRNAs, and use the 3 'UTR dual luciferase report system for target validation, aimed at the miRNA levels to explore postmenopausal osteoporosis molecular mechanism with kidney Yin deficiency syndrome.

Detailed Summary:
Sponsor: Fujian Academy of Traditional Chinese Medicine

Current Primary Outcome: microRNA expression lever in the Peripheral Blood [ Time Frame: one year ]

Original Primary Outcome: Same as current

Current Secondary Outcome:

Original Secondary Outcome:

Information By: Fujian Academy of Traditional Chinese Medicine

Dates:
Date Received: March 14, 2014
Date Started: February 2014
Date Completion: January 2015
Last Updated: April 30, 2014
Last Verified: March 2014